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  • Should the veterinary medical staff evaluate the health status of newly received animals?
  • What is the primary purpose of the IACUC?
  • What is particularly important for IACUC members serving as the lay member or the non-affiliated member?
  • Are alternate members allowed to attend IACUC meetings when their regular counterparts are present?
  • What must the IACUC ensure regarding alternatives to painful procedures?
  • When might an employee need to disclose financial interests according to conflict of interest policies?
  • For which species is an adjunctive method of euthanasia recommended due to difficulty in detecting heartbeat?
  • Is it necessary for VA employees to have prior permission for outside financial ventures?
  • Regarding inhalants, what precaution should be taken?
  • How is a significant deficiency perceived in the context of animal trials?
  • What is a required member type on the IACUC?
  • Which of the following is an incorrect statement regarding regulations?
  • Which function is NOT typically performed by the IACUC?
  • Which organization is referred to as the CDC?
  • How long can approval be maintained for non-USDA covered species?
  • What are the two IACUC review methods recognized by the USDA Animal Welfare Act Regulations and PHS Policy?
  • In the case where a faculty member demonstrated a blood sampling procedure not approved by the IACUC, to whom must the noncompliance be reported?
  • What training is not required for IACUC members according to the Guide?
  • True or False: DoD requires its facilities to be accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC).
  • Which department is abbreviated as DOD?
  • Can amendments just wait until the annual review?
  • Is the authority to stop animal activities exclusive to the IACUC?
  • Which of the following is NOT a reason to seek agency advice on conflicts of interest?
  • Which regulatory body does NOT mandate a scientific member on the IACUC?
  • Whom does the IACUC make recommendations about the animal program to?
  • Does every project have to undergo both annual and triennial reviews?
  • Does the VA require its Veterinary Associate (AV) to be present for the semiannual review?
  • What does AAALAC stand for?
  • Which outcome option is NOT available during designated review of animal protocols?
  • Can the CEO and the IO be the same individual?
  • What is the relationship between primary reviewers and designated reviewers in IACUC practice?
  • What is the principal danger of using inhalation agents for euthanasia?
  • Which of the following statements about euthanasia methods is incorrect?
  • Which regulatory body is primarily responsible for enforcing animal welfare standards in the U.S.?
  • The institution's program for the care and use of animals should include which of the following information?
  • What key aspect of semi-annual evaluations is emphasized by both USDA and PHS?
  • According to U.S. Government Principles, pain perceived by animals should be assumed in which situation?
  • Which of the following details is not required in a narrative when conducting a database search for alternatives to painful animal procedures?
  • How long is an IACUC approval valid for USDA covered species?
  • What is the maximum amount of time the IACUC has to report a failure to correct significant deficiencies to the USDA?
  • When reporting an IACUC suspension, what is the appropriate action?
  • Which of the following does not represent a reduction in animal use?
  • What essential area must training and instruction provide guidance on for personnel?
  • Which activity qualifies an animal for category E?
  • What should be the state of animal drinking water according to specific animal requirements?
  • Who must review and sign the semi-annual report?
  • Is it permissible for federal employees to endorse products using their Government position or title?
  • How often must the IACUC perform evaluations according to guidelines?
  • Which infection poses a significant risk to a human fetus?
  • What is the purpose of OHSP in research?
  • Which group monitors the conditions of procedure rooms?
  • True or False: The IACUC can extend protocol approval without a full committee review after the triennial review is due.
  • When there is a change in the name of the institution or its ownership, how many days does the institution have to notify the APHIS AC Regional Director?
  • What must be included in the annual report to OLAW for PHS-assured institutions?
  • What consequence can arise from a member not disclosing a conflict of interest?
  • What is the primary purpose of the Animal Care Section of the USDA?
  • Before the meeting, do IACUC members need access to full protocols?
  • What does the Animal Welfare Act Regulations say about reporting violations?
  • In a research environment, why is it important to quarantine before or after using specialized research areas?
  • Which aspect of care is the attending veterinarian required to oversee according to AWA Regulations?
  • Which organization is responsible for conferring CPIA certification?
  • Can the IACUC suspend animal activities that it has never reviewed?
  • Which statement regarding required IACUC members is false?
  • What must be taken into account regarding confidentiality and medical evaluations?
  • Which of the following is true about IACUC member training?
  • Under what circumstance is the IV or IC injection of potassium chloride an acceptable euthanasia method?
  • What types of protocols require administrative review and approval at the Component headquarters level in DoD research?
  • Should emergency veterinary care only be available during business hours?
  • Which institutions are required to comply with the PHS Policy?
  • What should an IACUC member do when they have a conflict of interest?
  • Is emergency veterinary care required to be available after work hours and on holidays?
  • Which disease is not easily transmitted to humans through animal bites?
  • Decentralization in research facilities can lead to increased exposure to disease agents due to what considerations?
  • According to VA policy, when using DMR, must all members receive complete copies of all protocol forms?
  • What happens if designated reviewers have differing opinions on modifications required for approval?
  • Which federal law mandates the PHS Policy?
  • In research contexts, what does PI refer to?
  • What is the purpose of the triennial review according to PHS Policy?
  • Although opinions vary about the level of detail needed in IACUC minutes, a typical standard is that IACUC minutes:
  • What is a requirement for an IACUC to allow for modifications before granting approval?
  • What is one of the best practice credentials for an Attending Veterinarian?
  • What is the initial process for designated-member review of new submissions?
  • In a DoD IACUC, what is the role of the veterinarian?
  • What is the minimum duration that records must be retained in DoD research?
  • Which of the following best describes the role of the Institutional Official (IO) in animal research?
  • Under what circumstances is it acceptable to store food and chemicals in the same refrigerator?
  • When conducting a semi-annual evaluation, what is the minimum number of IACUC members required to be present?
  • Which statement accurately reflects the definition of expedited review within the context of IACUC?
  • Which organization sets the regulations for the humane care and use of animals in research?
  • What is the primary focus of IACUC training for personnel?
  • What happens if an IACUC is not properly constituted?
  • Is there a requirement for the AV to pre-review protocols before IACUC submission in non-VA institutions?
  • What is the primary action by which physical methods of euthanasia cause death?
  • Which of the following does NOT need to be maintained by the IACUC?
  • The Guide for the Care and Use of Laboratory Animals states that those who care for or use animals must assume responsibility for what?
  • Feed and bedding should be:
  • Which regulation is commonly considered regarding the use of fillable forms for animal protocols?
  • Which statement regarding polling IACUC members is TRUE?
  • According to OLAW, what is considered a suspension?
  • Can the IACUC conduct formal business if a quorum is lost during a meeting?
  • Can any veterinarian serve on the IACUC?
  • What are the VA IACUC membership requirements based on?
  • What method is commonly used to monitor the effectiveness of an autoclave?
  • What is critical for animal welfare when assessing their environment in research?
  • What is the primary purpose of the IACUC in the context of animal research?
  • In which of the following cases would an alternate member be allowed to vote?
  • If a compliance incident involves USDA-covered animals, what must be reported to the USDA?
  • Which regulatory entity enforces the Animal Welfare Act?
  • What happens to containment and safeguard practices as the BSL and ABSL levels increase from 1 to 4?
  • Who is primarily responsible for developing a useful occupational health program?
  • What is the main role of IACUC alternates?
  • Who is typically defined as the CEO?
  • Is it acceptable to immerse aquatic species in carbon dioxide for euthanasia?
  • What authority must institutions provide to the Attending Veterinarian regarding veterinary care?
  • What is one objective of the annual report to the USDA/APHIS?
  • What space requirements for cats are included in the Animal Welfare Regulations?
  • Which of these IACUC protocol review outcomes is recognized in the USDA Animal Welfare Act Regulations and PHS Policy?
  • Who must participate in the semiannual review of IACUC programs and facilities?
  • Which entity does not require the IACUC to have a scientific member?
  • Which statement regarding the investigation of complaints is true?
  • What are the two criteria the IACUC should evaluate before suspending an animal activity?
  • Who must participate in the semiannual review according to VA rules?
  • Which policy prohibits IACUC members from voting on their own proposals?
  • Are alternates required to represent their regular members’ positions during voting?
  • What is the correct protocol if a disaster occurs and animals cannot be relocated?
  • What are the two main components of the semi-annual evaluation process?
  • Which statement regarding modifications to animal protocols after IACUC approval is TRUE?
  • What should IACUC members do when they have a conflict of interest regarding a proposal?
  • Which body is specifically tasked with reviewing animal research protocols?
  • Who has the legal authority to sign the USDA registration form of a research institution?
  • Which agency is responsible for deciding if a federal employee has violated conflict of interest statutes?
  • In which situation is serum collection and storage valuable?
  • The USDA Animal Welfare Regulations and PHS Policy emphasize the inclusion of which two components in the animal care evaluation?
  • Biosecurity measures in a research area may include which of the following?
  • What is a key responsibility of IACUC members during meetings?
  • In the event of IACUC criticism, which action is suggested for the institution?
  • What should a PAM staff member do if they find serious noncompliance?
  • Can a regular IACUC member have multiple alternates?
  • In outdoor housing, should animals have protection from harsh weather conditions?
  • What must be weighed when identifying humane endpoints in studies?
  • Which field does the American Association for Laboratory Animal Science focus on?
  • Do stocks held by a sector fund generally represent a disqualifying financial interest under 18 U.S.C. § 208?
  • What does GLP stand for in the context of laboratory practices?
  • What is not required by Animal Welfare Regulations for transport cages?
  • What primary aspect do institutional policies address regarding animal welfare?
  • What does ILAR stand for?
  • Which statement is false regarding shigellosis?
  • According to USDA Regulations, how many members from one administrative unit can an IACUC have at maximum?
  • Which of the following is not a recordkeeping requirement according to PHS?
  • What does ACLAM stand for?
  • Which statement regarding IACUC suspensions is false?
  • What is necessary for the IACUC to convene a meeting?
  • To whom does the IACUC report if the progress toward correcting significant deficiencies is lacking?
  • Why are inspections of animal use areas important in a PAM program?
  • Which statement about alternate IACUC members is false?
  • What is the primary mission of the Animal Welfare Information Center (AWIC)?
  • What two components must be included in the IACUC's semi-annual self-evaluation?
  • When an institution uses agricultural animals, what is a requirement for IACUC membership?
  • What duty is NOT assigned to the IO by the Animal Welfare Act Regulations?
  • What consequence can arise from violating ethics regulations?
  • What is the main problem caused by algae growth in an aquatic system?
  • What procedural action should be taken if an animal exhibits severe pain post-surgery?
  • What authority does the Institutional Official (IO) have regarding previously approved animal activities?
  • What is a typical standard for IACUC minutes?
  • Which act is enforced by the USDA-APHIS-AC?
  • Chloral hydrate is conditionally acceptable for euthanasia in large animals that are:
  • What does the acronym AWIC stand for?
  • Is it a requirement for IACUC members to have access to grant documents?
  • Which of the following is true regarding teleconferencing for IACUC meetings?
  • When conducting a semi-annual self-evaluation, how many IACUC members are needed?
  • If a grant is for longer than 3 years, can the triennial review period be extended?
  • What are the four categories of protocol reviews?
  • Who is responsible for signing the USDA/APHIS Annual Report?
  • True or False: The VA rules are less strict compared to USDA/PHS rules.
  • What accreditation is required by the VA?
  • How are protocols handled if designated members can neither all agree on approval nor modifications?
  • When is a designated reviewers system typically used?
  • In compliance with USDA regulations, the IACUC must inspect which areas?
  • Why is monitoring of dry-bulb temperatures critical in HVAC systems?
  • Which statement about the CEO and IO is FALSE?
  • What best practice should an IACUC follow when addressing concerns about animal care?
  • What is an indicator that a designated reviewer can begin their work?
  • What is the minimum number of designated reviewers required for a protocol using designated-member review?
  • What should an IACUC member do if they do not understand a scientific protocol during a meeting?
  • Flow Through systems in aquatic life support primarily rely on what type of water use?
  • What is the term for the immediate physical environment surrounding the animal in the primary enclosure?
  • Who does the IACUC notify upon finding deficiencies during their semiannual self-evaluation?
  • Which agency requires the semi-annual evaluation of the IACUC?
  • How often should enclosures and accessories be sanitized at minimum?
  • In best practices, how should IACUCs communicate the results of their investigations?
  • What happens if an institution experiences an adverse event related to its animal program?
  • Which of the following types of drugs relieve pain?
  • Which of the following documents is included in the PHS Institutional Assurance filing requirement?
  • What organization is represented by the acronym AALAS?
  • Which regulatory body's guidelines are followed for maintaining an effective IACUC?
  • What is required of all personnel involved in the care and use of animals in order to ensure high-quality science and animal well-being?
  • Should agents designed to mask animal odors be used in housing facilities?
  • Who is responsible for reporting infractions in DoD research?
  • How many members of the IACUC can come from the same administrative unit according to USDA regulations?
  • Following a semi-annual evaluation, how long does the IACUC have to address significant deficiencies?
  • What is the primary purpose of the IACUC's semi-annual evaluation?
  • Is the IO permitted to approve animal activities without IACUC approval?
  • What must be reported to AAALAC regarding the animal care and use program?
  • What allows for the loss of AAALAC accreditation according to the provided context?
  • What is considered a significant change to an animal use proposal?
  • Is the floor space occupied by food bowls and enrichment devices considered part of the total floor space?
  • Which of the following is NOT a required element of the semi-annual report according to AWAR?
  • When should you seek agency advice regarding potential conflicts of interest?
  • Which agency is known as the FDA?
  • What action must be taken if an IACUC member learns about a potential violation of the Animal Welfare Act?
  • What is the benefit of using physical methods over non-physical methods for euthanasia?
  • Which of the following is an example of a record that is NOT required by the IACUC to maintain?
  • Which term is defined in the Guide as "an aversive state in which an animal fails to cope or adjust to various stressors with which it is presented"?
  • How detailed should the USDA-required annual review be?
  • What should the IACUC do when there are allegations of concerns regarding animal care and use?
  • Which definition best describes euthanasia according to AVMA guidelines?
  • What serves as a biological filter in the life support systems for aquatic animals?
  • Which of the following is true regarding the dog exercise program mandated by USDA Animal Welfare Act regulations?
  • Which statement about laboratory requirements is false?
  • What is the maximum amount of extra caging that can be stored in a procedure room at one time?
  • Are room temperature settings for rodents typically set below their Lower Critical Temperature (LCT)?
  • For what purpose is maintaining gas flow for euthanasia after apparent death important?
  • Which of these is not part of the acronym used by the entity overseeing animal research safety?
  • Which document outlines policies regarding the care and use of laboratory animals?
  • Which statement about restraint devices in animal care is true?
  • How does OLAW define a suspension in relation to animal activities?
  • Which of the following statements is true regarding IACUC's triennial review of animal activities?
  • Must chlorine and chloramines be removed before use in aquatic systems?
  • Which agency's guidelines require compliance from institutions conducting animal research?
  • What is a permissible outcome of a full committee review (FCR)?
  • What is a quorum of a committee?
  • Which option best describes the IACUC's responsibilities?
  • For which scenario is veterinary consultation mandatory according to VA guidelines?
  • Which of the following statements about IACUC suspensions of animal activities is false?
  • Which IACUC responsibility involves the suspension of activity not following approved protocols?
  • What is required of institutions concerning health history in occupational health programs?
  • What must be done regarding significant changes to animal protocols after IACUC approval?
  • Should alternate members be included on IACUC rosters submitted to OLAW?
  • Who typically holds the title of Principal Investigator in a research study?
  • Who is the Executive Agent for the Department of Defense Directive number 3216.1?
  • Should the use of pesticides be recorded and coordinated with animal care staff?
  • What is the purpose of having an effective IACUC?
  • What term describes allergic reactions that occur within 10 to 15 minutes of exposure?
  • Which organization primarily focuses on public health and safety?
  • If the IACUC suspends an activity, what is a primary responsibility of the IO?
  • What is essential for conducting animal procedures causing pain or distress?
  • Which statement is TRUE regarding health requirements for shipping animals?
  • What is a regulation?
  • Which of the following is a key component of a post-approval monitoring program?
  • Which regulatory body requires annual reviews?
  • What should be avoided in the colloquial use of terms related to IACUC reviews?
  • Which statement best defines the role of the Attending Veterinarian in relation to animal care programs?
  • What must the IO submit to the USDA/APHIS regarding major survival surgical procedures on regulated animals?
  • Are significant deficiencies required to be reported to regulatory bodies immediately?
  • Which organization is abbreviated as PHS?
  • What should be the primary consideration when setting standards for animal care in a research facility?
  • Which US agency requires placing animals used in research into pain/distress categories?
  • If an investigator conducts category B, C, and D activities on the same animal, how should that animal be classified?
  • What does AWAR/AWR stand for?
  • What does AWA stand for?
  • Which department is chiefly involved in national defense matters?
  • What must the IACUC do to suspend an animal activity?
  • What is a requirement for non-affiliated IACUC members?
  • According to the 8th edition of the Guide, what must institutions have in place regarding occupational health?
  • Can one alternate member serve for multiple regular members in an IACUC?
  • What type of training should IACUC alternates receive?
  • What must occur within 5 business days according to DoD regulations when certain events happen?
  • Which of the following statements regarding the process of polling IACUC members via email is true?
  • What happens if the IACUC decides to suspend an activity?
  • Which statement regarding floor drains is true?
  • Which of the following is NOT a reason for formalizing a post-approval monitoring (PAM) program?
  • Which statement about IACUC membership is false?
  • What is one requirement laid out by USDA regulations for IACUC members?
  • For continuity in IACUC practices, which is essential for individuals involved?
  • What requirement does the Animal Welfare Act place on multiple survival surgery?
  • What is a mandatory requirement for the non-affiliated member within the IACUC according to the DoD?
  • A person supplying dogs to research is exempted from licensing with the USDA under which of the following conditions?
  • Are chlorine and chloramines safe for use in aquatic systems without modification?
  • How often must the IACUC meet according to the guidelines?
  • Which statement about IACUC confidentiality is false?
  • Do new forms have to be used for the triennial review?
  • What is the meaning of the acronym IACUC?
  • What is the implication of the term “conditional approval” in the context of IACUC reviews?
  • Which of the following statements about OLAW's guidance on the use of carbon dioxide as a euthanasia agent is false?
  • Which of the following statements about the use of "alternate" IACUC members is false?
  • How long must research institutions retain certain records for possible review after the completion of a project?
  • To which animals do VA rules apply?
  • Which action is NOT permitted by the Institutional Official according to USDA Animal Welfare Act Regulations and PHS Policy?
  • Can both a member and their alternate contribute to a quorum simultaneously?
  • What should the Attending Veterinarian consult the IACUC on?
  • What must animals have in a primary enclosure setup?
  • What defines a quorum for IACUC meetings?
  • Which agency requires an annual report of animals used categorized by pain/distress levels?
  • At a minimum, what is required for animals regarding their space in enclosures?
  • Under the Federal Technology Transfer Act, what is the maximum annual royalty payment an employee can receive for assigned intellectual property rights?
  • Euthanasia agents that act by way of hypoxia are not recommended for which type of animals?
  • What is the focus of IACUC's facility inspection component during evaluations?
  • How frequently must the IACUC evaluate the animal care program?
  • If the IACUC withholds approval, what must be included in the notification?
  • How frequently does the USDA conduct inspections of research facilities?
  • Why is it considered better for the IACUC to have an odd number of members?
  • For which of the following animals must health records be maintained?
  • What requirement must be fulfilled before an animal can be used in research?
  • What authority does the Attending Veterinarian have under AWAR?
  • Which of the following is crucial for effective IACUC protocol review?
  • What responsibility does the IACUC have in relation to animal studies?
  • Which of the following statements is true regarding statutes?
  • What is the typical minimum level of detail required in IACUC meeting minutes?
  • What activity would disqualify an animal from USDA category D?
  • What does the term primary enclosure mean?
  • What is required in Animal Welfare Regulations for housing guinea pigs and/or hamsters?
  • Which statement is TRUE about exercise plans for dogs?
  • In the VA system, who is involved in the appointment process for the IACUC?
  • What document oversees the responsibilities of the IACUC within an institution?
  • What is NOT included in the program review portion of the semi-annual IACUC evaluation?
  • The acronym NRC is commonly known as what?
  • When is the use of chemical restraint in animal studies permissible?
  • Which mandate requires occupational health services for employees in animal facilities?
  • What is a key reason for having alternates in the IACUC?
  • Which statement about the CEO and IO is false?
  • Which is one of the key responsibilities of the IACUC?
  • What is not a recommended method to prevent Q fever infection in laboratory workers?
  • Which of the following statements is TRUE?
  • Should facilities have a disaster plan for animals?
  • Who are essential voting members of the IACUC?
  • How is a quorum defined in relation to conducting official IACUC business?
  • What is primarily enforced by the Occupational Safety and Health Administration?
  • What is a typical responsibility of the Attending Veterinarian concerning necropsies?
  • Which of the following statements is true regarding review outcomes in full committee review versus designated review of animal protocols?
  • What benefit does a formalized PAM program provide regarding compliance monitoring?
  • What is the correct procedure regarding ACURO review and IACUC approval?
  • Dogs obtained from a Class B dealer may originate from which of the following sources?
  • Which situation requires the full IACUC committee's review rather than Designated Member Review?
  • What does "suspension" mean in the context of animal activities?
  • What is the purpose of a semiannual review by the IACUC?
  • Which of the following is NOT a component of the veterinary care program?
  • Can designated-member review be utilized for new submissions?
  • What does EPA stand for?
  • Why is it critical that IACUC members attend meetings regularly?
  • Which of these IACUC protocol review outcomes are recognized in the USDA Animal Welfare Act Regulations and PHS Policy?
  • To comply with the law, who must review and sign the IACUC semi-annual self-evaluation report?
  • According to the PHS policy, any building, room, or area used for confinement, transport, or experiments including surgery is considered an animal facility if the animals are maintained there for more than ______ hours.
  • What is the proper sequence for a designated member review by the IACUC?
  • When the initial characterization of a GMA reveals a condition that negatively affects animal well-being, what should be reported to the IACUC?
  • To violate Section 208, what must be true regarding the employee's financial interest?
  • Which is an example of appropriate enrichment for a guinea pig?
  • Who is referred to as the IO?
  • What is the correct usage of carbon monoxide in euthanasia?
  • When must veterinary consultation occur?
  • Are occupational health and safety programs intended to protect employees in animal facilities required to be the same at all institutions where research animals are housed?
  • Post semi-annual evaluation, who must review and sign the report to comply with AWAR?
  • What is the required action if a significant deficiency is not corrected according to the IACUC semi-annual evaluation report?
  • What is the full form of DHHS?
  • What is the recommended procedure for removing soiled cages from a procedure room?
  • If multiple designated reviewers are involved and one calls for a full committee review, what is the outcome?
  • What fundamental role does an IACUC-approved PAM program serve?
  • How should euthanasia agents that induce hypoxia be viewed in regards to certain animal groups?
  • What is the maximum weight for performing cervical dislocation on a rabbit?
  • What should IACUC minutes allow for an outside observer to do?
  • What is the role of the Institutional Official regarding animal-use projects?
  • What is necessary for significant changes to animal protocols after IACUC approval according to policy?
  • What must the IACUC do if a concern is raised regarding animal care?
  • What kind of corrective actions is the Component headquarters responsible for overseeing?
  • How frequently does the PI need to reconsider alternatives?
  • What documents are mandated as the basis for the IACUC semi-annual evaluation?
  • What does the acronym IRAC stand for in the context of animal research?
  • What is not a best practice for IACUC members?
  • According to PHS policy, how often must assurance renewal occur?
  • What is a primary role of IACUC members during protocol discussions?
  • Which of the following statements about an HVAC system is FALSE?
  • What outcome option is available in full committee review but not designated review of animal protocols?
  • Is it acceptable to hold excess equipment in a procedure room as long as the equipment is covered?
  • Which two institutional administrators are specifically dealt with in regulations?
  • What should be done immediately after allegations of improper animal care are made?
  • When conducting a semi-annual evaluation, how many IACUC members must be present?
  • Which statement regarding the responsibilities of the Institutional Official (IO) is false?
  • What are three components that must be described in the Animal Welfare Assurance?
  • What is considered best practice for the IACUC Chairperson?
  • Which statement regarding dermatomycosis is correct?
  • What is the main purpose of performance standards in compliance regulations?
  • Which of the following is not an example of replacement in animal research?
  • In what aspect can the IACUC's authority be described?
  • Which transmission mode is not considered major for the herpes B-virus?
  • Which factor is essential when designing HVAC systems for research facilities?
  • Which of the following best describes how minority opinions should be recorded?
  • In terms of refinement, which option does not qualify?
  • Principal investigators are discouraged from advocating for animal reuse as a reduction strategy because it should not be a rationale for what?
  • What does NSF stand for in research funding?
  • If a significant deficiency is not corrected as per the IACUC timeline, what action must be taken?
  • The three Rs of Russell and Burch promote which principles in research?
  • How should IACUC minutes be structured to ensure transparency?
  • Which statement about barbiturates is true?
  • What does the acronym AC refer to in the context of animal care and regulation?
  • Is it ethically acceptable for a federal physician to accept a payment for a presentation on their research to a non-profit organization?
  • Which term is defined as measures to control known or unknown infections in laboratory animals?
  • Which outcomes are recognized in IACUC protocol reviews according to regulations?
  • Which regulation ensures that veterinary care is provided even when an attending veterinarian is unavailable?
  • What key information must be included in an IACUC semi-annual self-evaluation report regarding deficiencies?
  • Which behavior does NOT support effective IACUC protocol review?
  • When should the IACUC and IO report a suspension?
  • What role does the Institutional Official (IO) play in the evaluation process?
  • What is the recommended concentration of carbon monoxide used for euthanasia of small mammals?
  • Under which circumstance may animal work commence before IACUC approval is received?
  • If a VA researcher conducts research after hours, can a VA non-profit research corporation supplement the employee's salary for the work?
  • If the IACUC votes to withhold approval, can it reconsider its decision?
  • What is an ineffective way to identify hazards in a lab setting?
  • Can the same pool of alternate members be used for multiple regular IACUC members?
  • How frequently should biological safety cabinets be certified?
  • Which entity is required to release information under the Freedom of Information Act?
  • Which entity is responsible for enforcing the Health Research Extension Act?
  • Which statement about IACUC suspensions of animal activities is false?
  • Which of the following is typically not included in preventative medicine programs?
  • Which is NOT a main objective of the Guide?
  • What level of authority must the IACUC have to fulfill its responsibilities?
  • Why should an IACUC consult with the Attending Veterinarian?
  • What is not a required inclusion in the VA semiannual program review report?
  • Which of the following offers a voluntary accreditation program of institutional animal care and use programs?
  • Which statement about inhalant agents used for euthanasia is true?
  • What can happen if a federal employee violates regulations?
  • What are used to standardize methods for performing specific institutional practices?
  • What are two review methods allowed by the USDA and PHS?
  • Can animals remain in a lab until a protocol expires or they are euthanized?
  • Which animal areas are required to be inspected?
  • What must the IACUC do if a majority of a quorum votes to suspend research activities?
  • Can a non-affiliated member of the IACUC be a scientist?
  • Which member type is emphasized for their input in IACUC meetings?
  • When designing a PAM program, which factors should be considered?
  • Do animal protocols need pre-review according to regulations?
  • Which of the following is NOT a category of Aquatic Life Support Systems?
  • PHS Policy __________ an occupational health and safety program for PHS-assured institutions.
  • What is the shelf life for feed that is fortified with non-stabilized vitamin C?
  • What type of practices does GLP refer to?
  • What is required of institutions concerning animal welfare concerns?
  • What does the term 'silence' signify in the context of IACUC review processes?
  • What is a necessary condition for an institution to notify the Component headquarters?
  • True or False: The AWAR provides protections for whistleblowers who report violations.
  • Which of the following statements about minority opinions in IACUC meetings is correct?
  • How often must the IACUC review the animal care program and facilities?
  • When reporting an IACUC suspension of an animal activity, what should the IACUC do?
  • What action must the institution take if notified by USDA of an investigation?
  • What is expected of designated reviewers regarding the consensus on a protocol?
  • What term refers to the physical structure that contains both the water and the animals used in research?
  • Under what conditions would a semiannual report need to be submitted to OLAW?
  • The participation of personnel in Occupational Health and Safety Programs should be based on what factors?
  • How often should personnel who have contact with nonhuman primates be screened for tuberculosis?
  • Which of the following must be part of the corrective action plan for deficiencies?
  • In research protocols, how should surgery on regulated animals be handled?
  • What is false regarding conditional approval in IACUC protocols?
  • Who is responsible for ensuring that the amendments are reviewed before implementation?
  • What is the role of a non-affiliated member in the IACUC?
  • Which animals require the same minimum cage height recommendations in the Guide?
  • Which of the following is NOT a responsibility of the IACUC?
  • Which of the following agencies is responsible for regulating food safety?
  • What is the relationship between a VA IACUC and an affiliate IACUC?
  • Do VA rules require that vet pre-review occur for all animal protocols before IACUC review?
  • If IACUC members have conflicts of interest, what is the best practice regarding protocol voting?
  • Can squirrel monkeys transmit herpesviruses to owl monkeys?
  • The failure position of valves controlling reheat coils is designed to promote what condition?
  • Which area is expected to have the same standards and care as animal procedure rooms?
  • What organization is associated with enforcing PHS Policy?
  • Which military branch governs the DoD Veterinary Services Program?
  • Which body requires the reporting of uncorrected significant deficiencies?
  • Single housing of social species should be justified by what criteria?
  • What does the IO need to ensure about the animal care program?
  • True or False: IACUC members cannot participate in the review of activities they are personally involved in.
  • Notifying investigators of IACUC protocol review outcomes in writing is:
  • Which composition of members is required for an IACUC to comply with USDA Animal Welfare Act Regulations and PHS Policy?
  • Who is responsible for monitoring the expiration date of drugs stored in a procedure room?
  • Under which legislation are animals excluded from coverage, including Rattus and Mus?
  • Who has the authority to stop animal activities in an institution?
  • What aspect of animal care may be the focus of IACUC scrutiny?
  • Which of the following statements accurately describes the importance of the IACUC?
  • What percentage of royalty payments can federal employees receive from government-assigned inventions under the Federal Technology Transfer Act?
  • What happens when all members agree to DMR during the decision-making period?
  • What is the consequence of failing to disclose conflicting financial interests?
  • What do the record-keeping requirements of the Animal Welfare Regulations specify about IACUC records?
  • What does the term "Thermoneutral Zone" (TNZ) refer to?
  • What does DMR stand for in IACUC terminology?
  • To conduct official business in a meeting, a quorum of voting members must:
  • Which studies require special consideration according to common practices?
  • What should be avoided in an animal's resting area within an enclosure?
  • What best describes the required composition of a 5-member IACUC?
  • Which area must personnel training and instruction cover?
  • What is the role of the Institutional Official (IO)?
  • What is the proper protocol for designated reviews by the IACUC?
  • Who is responsible for ensuring that personnel working with live animals are properly trained?
  • Which agency ensures that research involving animals is conducted ethically?
  • Which of these statements is true concerning the USDA Animal Welfare Act?
  • What is NOT one of the responsibilities of individual IACUC members?
  • Which entity often uses the term "Attending Vet"?
  • What is considered best practice regarding institutional reporting practices?
  • How is confirmation of death determined after euthanasia?
  • Which organization enforces regulations pertaining to animal welfare in research environments?
  • Which function is not typically performed by the IACUC?
  • What does the term 'semiannual review report' refer to in DoD regulations?
  • In special circumstances, what is the determining factor for deviating from AVMA guidelines?
  • How strict are the annual and triennial deadlines for protocol reviews?
  • Notifying investigators of IACUC protocol review outcomes in writing is:
  • To comply with the USDA Animal Welfare Act Regulations, what is the proper IACUC course of action to follow if a significant deficiency is not corrected according to the plan set forth in the IACUC semi-annual evaluation report?
  • During an IACUC meeting, what is necessary for documentation in the minutes regarding a withheld approval?
  • Is the attendance of the Attending Veterinarian mandatory for the IACUC to conduct its business?
  • According to the Ag Guide, which is not a requirement for IACUC membership?
  • Which animals are specifically excluded from the AWA?
  • What is a true statement about routes of administration for injectable agents?
  • Which entity generally oversees the process of ensuring compliance with animal welfare standards in research facilities?
  • What agency does NIH represent?
  • What type of drug must be used with neuromuscular blocking agents?
  • What should a federal physician do before recruiting VA patients for a clinical study to ensure compliance with ethics statutes?
  • Which regulatory body requires detailed three-year (triennial) reviews?
  • Must a non-affiliated member be present for the IACUC to conduct its business?
  • What is a potential disadvantage of a passive PAM program?
  • What is the minimum number of voting members required for the IACUC?
  • Can the VA grant waivers for employees to participate in particular matters without disqualifying financial interests being substantial?
  • Which position holds the administrative authority to commit resources for animal care compliance?
  • How often must the IACUC conduct semiannual inspections?
  • What statement accurately describes an active PAM program?
  • To whom is the semi-annual report submitted as per both AWAR and PHS Policy?
  • According to the Guide, which statement is true regarding the use of non-pharmaceutical grade chemicals?
  • What does FASS stand for in the context of animal science?
  • Which statement best reflects the relationship between IACUC approval and animal work initiation?
  • Institutions should use the recommendations in the Guide as what?
  • According to VA rules, who is mandated to serve as the Institutional Official (IO)?
  • What is a true statement regarding physical methods of euthanasia?
  • Which line of authority is responsible for submitting the annual report to OLAW?
  • In the context of reheat coils in HVAC systems, what is the correct position for valves to fail?
  • Which group of animals is primarily covered by the USDA/AWA?
  • Which of the following outcomes is considered a valid response in a designated review?
  • The IACUC may suspend an activity only after what condition has been met?
  • What change was made to the Animal Welfare Act by the 1990 pet protection amendment?
  • When should you stop using a sharps container?
  • What action should the IACUC take if an investigator mistakenly euthanizes animals using a method not approved in the protocol?
  • How long must animals be housed for an area to be included in the IACUC's semi-annual evaluation?
  • Who has the authority to determine the time frame for requesting a full committee review (FCR)?
  • Which of the following is NOT required when filing a PHS Institutional Assurance?
  • What is the acceptable range for maintaining dry-bulb temperatures according to HVAC standards?
  • What is a critical aspect regarding the use of primary reviewers?
  • Can alternates participate in IACUC activities if their regular member is present?
  • Which of the following is NOT a criterion for the Attending Veterinarian?
  • Which official must approve changes to the animal care program?
  • True or False: All required members of the IACUC must be voting members.
  • How should personnel training in animal care programs be managed?
  • What are the recognized review methods by the USDA Animal Welfare Act and PHS Policy?
  • If a PHS assured institution is not AAALAC accredited, what must be included in the annual report to OLAW?
  • What is a characteristic of an effective veterinary care guide within a PAM program?
  • What should happen if an alternate member wishes to vote during a meeting?
  • When must all personnel performing animal procedures be properly trained?
  • Which statement about polling IACUC members is correct?
  • Who serves on the IACUC by virtue of their employment status?
  • How can one identify a hazardous area within a facility?
  • Which of the following statements regarding mouse allergen is true?
  • If a significant deficiency is NOT corrected according to the IACUC semi-annual evaluation report, what is the proper course of action?
  • Which role is typically not filled by an IACUC member?
  • What should non-scientist IACUC members do during meetings?
  • Are alternate members specifically addressed within AWAR or PHS Policy?
  • Which of the following entities does NOT report directly to the IO?
  • If an institutional official halts an animal activity, can they reinstate it without IACUC involvement?
  • Who must be notified of IACUC decisions to approve, withhold approval, or require modifications?
  • When selecting proper equipment for facilities, which of the following should not be a primary consideration?
  • What role does the attending veterinarian play in IACUC activities?
  • Which of the following is NOT a responsibility of the attending veterinarian or designee?
  • Do individual members of the IACUC have the authority to stop animal activities?
  • Is it permissible for a non-affiliated member of the IACUC to be a veterinarian?
  • What information is required in the report for deficiencies identified during IACUC evaluations?
  • What is the primary goal of the Guide for the Care and Use of Laboratory Animals?
  • Which document specifies fines for IACUC members who violate confidentiality regulations?
  • Which of the following roles is NOT specified by USDA AWAR?
  • Who has the authority to approve a course of action following an IACUC investigation?
  • What is the correct procedure regarding IACUC member voting?
  • What defines a significant deficiency in the IACUC semi-annual report?
  • How should hazardous wastes be handled before removal from the facility?
  • What is the expected frequency for cleaning a procedure room?
  • According to USDA Regulations, an IACUC may have no more than how many members from any one administrative unit?
  • Under what circumstances must USDA/APHIS be informed of a suspension of animal activities?
  • Which of the following information need not be present on an official tag?
  • What type of event must be reported as adverse regarding IACUC protocols?
  • What action should be taken if a research project is found to be in significant noncompliance?
  • Who is responsible for signing the Assurance?
  • According to AWAR, can any IACUC members be denied participation in the semi-annual evaluation?
  • What must the IACUC do if a temporary hold leads to a majority vote suspension?
  • What is the primary purpose of regulations in relation to statutes?
  • Which of the following statements about the USDA Animal Welfare Regulations and allegations of improper animal care is false?
  • When selecting a suitable social environment for animals, what two characteristics must be considered?
  • Who has the authority to approve amendments to protocols involving specific animal types in DoD research?
  • What are the two categories of deficiencies reported in the semi-annual report?
  • What is a necessary quality for the IACUC Chairperson regarding parliamentary procedure?
  • Which body can the IACUC consult when concerns about animal welfare arise?
  • Can DoD researchers inflict wounds on animals for training purposes?
  • Who is responsible for oversight of the DoD animal use program?
  • Does distress always cause immediate observable changes in animals?
  • How often must the IACUC perform an annual review of a protocol?
  • Who is responsible for appointing alternate members in the IACUC?
  • Who is primarily responsible for monitoring health and safety procedures in a laboratory animal program?
  • Do employees of VA non-profit research corporations have to follow the same conflict of interest statutes as federal employees?
  • When a federal employee licenses an invention to a private company, can they continue to work on that invention while on government duty?
  • In the absence of IACUC approval, can any other body or official approve an animal protocol?
  • What critical factor requires special attention when utilizing decentralized research facilities?
  • What options do designated reviewers have during their review?
  • When using CO2 for euthanasia, what should be maintained after apparent death?
  • In the case of three or more designated reviewers, what is required for a decision to be made?
  • What must a facility do if it is not able to meet the requirements for animal housing?
  • What does OSHA stand for?
  • What is necessary when alternates participate in IACUC meetings?
  • How is distress defined in the context of animal welfare?
  • Which of the following is not considered a hazardous property of a chemical?
  • Which role is considered essential for all IACUC protocols and operations?
  • What activity would disqualify an animal from USDA category B?
  • What is the purpose of the IACUC self-evaluation?
  • In terms of animal welfare, what does the term 'warm-blooded animals' refer to?
  • What pressure should areas designated for surgery or clean equipment storage ideally maintain?
  • Areas for quarantine, hazardous substance studies, and nonhuman primate rooms should be kept at ______________ pressure.
  • In which scenario would the IACUC require a significant review process?
  • According to the PHS Policy, the definition of animal includes which of the following?
  • What is the general standard for details in IACUC minutes?
  • What is one of the primary responsibilities of the IACUC?
  • Which of the following is the best definition of a laboratory animal?
  • Which regulation prohibits reprisal against individuals reporting violations in animal care?
  • Which of the following statements reflects how institutions should prioritize animal care efforts?
  • Which members must be present for the IACUC to conduct business according to DoD regulations?
  • True or False: The IACUC has no real authority to suspend animal activities.
  • Which regulations must Department of Defense (DoD) researchers adhere to?
  • Which of the following circumstances must be reported promptly to USDA?
  • Why is appropriate training crucial for researchers conducting surgeries?
  • What determines cage space requirements for nonhuman primates as outlined in the Animal Welfare Regulations?
  • What is one requirement for the IACUC chair according to USDA regulations?
  • When conducting research outside of the United States, do DoD researchers need to comply with local regulations?
  • Veterinarians providing clinical oversight should possess what qualifications?
  • When conducting the facilities inspection portion of the semi-annual evaluation in compliance with both the USDA Animal Welfare Act Regulations and PHS Policy, the IACUC must include:
  • Which of the following is a required member of the IACUC?
  • Can a federal researcher represent a company licensing an invention in matters involving the U.S. government?
  • What is the minimum number of members required for a DoD IACUC?
  • What virus causes a disease similar to smallpox but is less severe?
  • Who appoints the IACUC members?
  • What does the acronym IRAC stand for in the context of animal research?
  • Animal Welfare Regulations for rabbits require:
  • Which hazard is addressed with the use of bite and scratch emergency kits?
  • Which of the following statements about IACUC confidentiality is false?
  • Which of the following statements regarding IACUC members is true?
  • Who primarily oversees compliance with the Animal Welfare Act?
  • What is a required member of the IACUC?
  • What constitutes a quorum in the IACUC context?
  • Which category of Aquatic Life Support Systems involves constant recycling of water?
  • True or False: According to the 2011 Guide, a Chair is considered an essential member.
  • In collaborative animal use situations, what is necessary regarding responsibilities?
  • What are considered "significant changes" that require a review of an amendment?
  • Which reporting line does OLAW recommend for an animal care and use program?
  • What is the first step in a designated IACUC review?
  • Who is responsible for appointing members to serve on the IACUC?
  • What action should be taken regarding unsanitary conditions identified in laboratories?
  • Is a formal Post Approval Monitoring program required by PHS Policy?
  • Who has the authority to determine if a deficiency identified during an IACUC evaluation is significant or minor?
  • Regarding IACUC review outcomes, which statement is TRUE?
  • How are the best practices for designated reviews typically sequenced?
  • Which statement accurately describes an expectation from IACUC regarding protocol compliance?
  • What action must be taken when using chlorine in aquatic systems with animals?
  • Personnel training and instruction must include guidance in which area?
  • PHS institutional Assurance is approved for a maximum of how many years, while USDA registration is updated every how many years?
  • Which of the following is NOT a requirement for IACUC minutes?
  • Which regulatory body mandates that the IACUC must have a Chairperson?
  • What action should be taken following the suspension of an animal activity by the IACUC?
  • Which statement is false regarding the Occupational Health and Safety Program?
  • Are WOC (Without Compensation) employees covered by ethics statutes?
  • How is the IACUC's membership determined?
  • Can an IO suspend IACUC approved activities?
  • When reporting an IACUC suspension of an animal activity, the IACUC should:
  • The AWA Regulations require that the attending veterinarian must:
  • What are the main goals of the semi-annual evaluation of the IACUC?
  • Which procedure is correctly associated with Designated Member Review?
  • What statement is true regarding the effects of anesthetics?
  • Which statement best reflects the operation of an effective IACUC regarding minority opinions?
  • Are designated members allowed to withhold approval for a protocol?
  • Which action is NOT permitted by the IO according to Animal Welfare Regulations and PHS policy?
  • Does the VA VMO have to be a full-time position?
  • What is a key benefit of utilizing designated-member review in IACUC protocols?
  • What is necessary for the IACUC to report a suspension effectively?
  • Which entity enforces the AWA?
  • What should the selection of analgesics and anesthetics reflect?
  • Life support systems are usually one of three types: re-circulating, flow-through, or ____________________.
  • How detailed should the PHS-required three-year review be?
  • Who is ultimately responsible for the animal care and use program?
  • Which of the following is NOT a role of the attending veterinarian?
  • What options do IACUCs have if additional information is provided by a PI after a decision to withhold approval?
  • What is the minimum requirement for access to drinking water for animals?
  • What action is not a duty of the IACUC during an investigation?
  • Which aspect of facility design is emphasized in the Guide for animal care?
  • During a euthanasia procedure, if an animal exhibits a reflex movement, what does it indicate?
  • Which of the following does NOT need to be maintained by the IACUC?
  • Who is responsible for the ethical treatment of animals in research at an institution?
  • For how long should records be kept according to PHS and AWRs?
  • Is it mandatory for sanitary measures to be applied at least every two weeks?
  • What does the Ag Guide refer to?
  • Is a quorum necessary for the semi-annual evaluation according to AWAR?
  • What is the required composition of IACUC members for compliance?
  • What does the term "polling" refer to in the context of IACUC operations?
  • What is necessary for a biofilter to effectively process bioload?
  • Under what circumstance would designated-member review result in a full committee review being called?
  • On behalf of an institution, which individual is ultimately responsible for compliance with PHS Policy?
  • According to the PHS Policy, can the non-affiliated member and the nonscientific member of the IACUC be the same person?
  • What is the primary function of an Aquatic Life Support System?
  • What kind of training must IACUC members undergo according to the Guide?
  • Regarding IACUC meeting attendance, which statement is false?
  • What is the mechanism of action of an overdose of barbiturates for euthanasia?
  • Which statement about the responsibilities of the Institutional Official (IO) is incorrect?
  • Which two aspects are mandatory in Disaster Planning and Emergency Preparedness?
  • What type of identification is not acceptable for dogs or cats at acquisition?
  • Which classification system is primarily based on USDA pain/distress categories?
  • Which policy states that IACUC members may not contribute to a quorum when reviewing their own protocols?
  • What is the organization whose guidelines on euthanasia are required by the PHS Policy?
  • What is a characteristic feature of Static Aquatic Life Support Systems?
  • DoD rules apply to which type of animals?
  • According to USDA regulations, failure to correct a significant deficiency must be reported within how many days by whom?
  • Regarding IACUC use of review outcomes such as "approval pending," "conditional approval," or "deferred," which of the following is false?
  • Are restraint devices considered a normal method of housing for animals?
  • Where should the USDA annual report be sent?
  • What role does the Institutional Official (IO) have regarding the semi-annual report?
  • What is one responsibility of IACUC members concerning animal care protocols?
  • Which document governs the humane care of animals in research according to these regulations?
  • What should the IACUC assess before allowing an animal activity to continue?
  • What does the PHS Policy state about the use of the Guide for the Care and Use of Laboratory Animals by institutions receiving federal funding for research?
  • Which statement concerning IACUC suspensions is false?
  • Which of the following members is required in a PHS-compliant IACUC?
  • Which of the following is not an IACUC activity?
  • Who should you discuss potential outside payment and royalty opportunities with to protect yourself from penalties?
  • As a VA employee, are you required to disclose intellectual property to the VA?
  • Which of the following statements is false concerning prolonged restraint of animals?
  • Which agency regulates the use of radioisotopes?
  • Which of the following statements regarding performance standards is FALSE?
  • What does the acronym APHIS stand for?
  • Who is authorized to conduct Post-Approval Monitoring (PAM)?
  • Who decides if a deficiency is classified as significant or minor?
  • What action should be taken if an IACUC member has a direct financial interest in a protocol?
  • What does Post Approval Monitoring entail?
  • Can members of the IACUC hold more than one role at the same time?
  • What must be included in IACUC meeting minutes?
  • Which document outlines the importance of confidentiality for IACUC members?
  • What does the Animal Welfare Act Regulations state regarding IACUC members reporting violations to USDA?
  • What is the primary goal of the IACUC in animal research settings?
  • Reports prepared by the IACUC during semiannual facilities inspections must distinguish between minor and significant deficiencies. Which of the following best describes a significant deficiency?
  • What is the maximum amount a federal employee’s family can own in a sector mutual fund to recommend purchasing drugs from a pharmaceutical company?
  • What is one of the primary focuses of AWIC?
  • What record must be kept by research facilities according to USDA Regulations?
  • Who has the authority to assign designated reviewers when designated-member review is applied?
  • What happens if a PI fails to complete the triennial review by the deadline?
  • Which codes and policies emphasize animal research as a moral imperative?
  • What document does the USDA require to be used as the basis for the semi-annual evaluation?
  • What organization does ACLAM represent?
  • The IACUC may suspend an activity only after?
  • What is required before conducting surgery regarding antinociception?
  • Which of the following provides voluntary accreditation for animal care programs?
  • Which combination is required for IACUC members according to PHS policy?
  • Record-keeping requirements of the Animal Welfare Regulations state that:
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